Journal article

A Novel Quantitative Simple Brain Metric Using MR Imaging for Preterm Infants

S Nguyen The Tich, PJ Anderson, JS Shimony, RW Hunt, LW Doyle, TE Inder

AMERICAN JOURNAL OF NEURORADIOLOGY | AMER SOC NEURORADIOLOGY | Published : 2009

Abstract

BACKGROUND AND PURPOSE: The application of volumetric techniques to preterm infants has revealed brain volume reductions. Such quantitative data are not available in routine neonatal radiologic care. The objective of this study was to develop simple brain metrics to compare brain size in preterm and term infants and to correlate these metrics with brain volumes from volumetric MR imaging techniques. MATERIALS AND METHODS: MR images from 189 preterm infants <30 weeks' gestational age or <1250 g birthweight scanned at term-equivalent age and 36 term infants were studied. Fifteen tissue and fluid measures were systematically evaluated on 4 selected sections. The results were correlated with tot..

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