Journal article

Effect of ThinPrep preparation on human papillomavirus detection and genotyping in rectal samples by PCR

SN Tabrizi, MP Stevens, MT Van Leeuwen, CM Vajdic, LP Botes, G Medley, R Hillman, A Grulich, SM Garland

Journal of Clinical Microbiology | AMER SOC MICROBIOLOGY | Published : 2009

Abstract

Specimen-to-specimen carryover during ThinPrep slide preparation was evaluated by comparing human papillomavirus genotypes detected prior and subsequent to the ThinPrep processing of 121 PreservCyt samples. Overall, 52 samples generated concordant genotypes and 38 had additional and 21 had fewer genotypes postprocessing. PreservCyt samples should be aliquoted for PCR testing prior to ThinPrep processing. Copyright © 2009, American Society for Microbiology.

University of Melbourne Researchers