Journal article

Psychiatric disorders and depression in multiple sclerosis outpatients: impact of disability and interferon beta therapy

GM Galeazzi, S Ferrari, G Giaroli, A Mackinnon, E Merelli, L Motti, M Rigatelli

NEUROLOGICAL SCIENCES | SPRINGER-VERLAG ITALIA SRL | Published : 2005

Abstract

Associations between psychopathology and gender, duration of MS, disability and therapy with beta-interferons were studied in multiple sclerosis (MS) outpatients. A controlled descriptive epidemiological study was carried out in two Italian outpatient MS centres on 50 outpatients with clinically definite relapsing-remitting MS presenting for regular follow-up and 50 healthy controls matched for sex, age and educational level. Subjects were assessed with the Structured Clinical Interview for DSM-IV (SCID I), the Beck Depression Inventory (BDI) and the State Trait Anxiety Inventory (STAI). MS patients reported a higher prevalence of psychiatric disorders (odds ratio 3.17), with 46% (n=23) suff..

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