Journal article
Comparison of QuantiFERON-TB Gold In-Tube Test and Tuberculin Skin Test for Identification of Latent Mycobacterium tuberculosis Infection in Healthcare Staff and Association Between Positive Test Results and Known Risk Factors for Infection
Paul Vinton, Seema Mihrshahi, Paul Johnson, Grant A Jenkin, Damien Jolley, Beverley-Ann Biggs
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY | CAMBRIDGE UNIV PRESS | Published : 2009
DOI: 10.1086/595695
Abstract
OBJECTIVE: We compared a whole-blood interferon-gamma release assay (QuantiFERON-TB Gold In-Tube test, hereafter "QFT-in tube test") with a tuberculin skin test (TST) to determine which test more accurately identified latent Mycobacterium tuberculosis infection in healthcare staff. METHODS: A total of 481 hospital staff members were recruited from 5 hospitals in Melbourne, Australia. They provided information about demographic variables and tuberculosis (TB) risk factors (ie, birth or travel in a country with a high prevalence of TB, working in an occupation likely to involve contact with M. tuberculosis or individuals with TB, or being a household contact of an individual with a proven case..
View full abstractGrants
Funding Acknowledgements
Department of Human Services Victoria ( Public Health Research Projects grant to B.-A. B.); National Health and Medical Research Council (scholarship to P. V.); Edgar Tattnall Memorial Trust ( grant to B.-A. B.).