Control of visually guided saccades in multiple sclerosis: Disruption to higher-order processes
Joanne Fielding, Trevor Kilpatrick, Lynette Millist, Owen White
NEUROPSYCHOLOGIA | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2009
Ocular motor abnormalities are a common feature of multiple sclerosis (MS), with more salient deficits reflecting tissue damage within brainstem and cerebellar circuits. However, MS may also result in disruption to higher level or cognitive control processes governing eye movement, including attentional processes that enhance the neural processing of behaviourally relevant information. The attentional control of eye movement was investigated in 25 individuals with MS and a comparable number of neurologically healthy individuals matched for age and IQ. This entailed an evaluation of distractor-related effects on the generation of both unpredictable and predictable visually guided saccades, as..View full abstract
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Awarded by National Health and Medical Research Council of Australia
This research was supported by a Fellowship awarded by the National Health and Medical Research Council of Australia (#454811) to Dr J Fielding.