Effect of the non-steroidal anti-inflammatory drug, carprofen, on weaned sheep following non-surgical mulesing by intradermal injection of cetrimide
IG Colditz, JB Lloyd, DR Paull, C Lee, A Giraudo, C Pizzato, AD Fisher
AUSTRALIAN VETERINARY JOURNAL | WILEY-BLACKWELL PUBLISHING, INC | Published : 2009
OBJECTIVE: To assess in weaned lambs the palliative effects of the non-steroidal anti-inflammatory drug, carprofen, following intradermal injection of cetrimide to induce non-surgical mulesing. PROCEDURES: We allocated 40 weaned lambs (20-22 weeks old) to four groups of 10 animals: (1) control, 2) conventional surgical mules, (3) intradermal treatment and (4) intradermal treatment + carprofen. Non-surgical mulesing was induced by intradermal injection of 4% (w/w) cetrimide + 3% (w/w) polyvinylpyrrolidone in water. In group 4, carprofen (4 mg/kg, SC) was administered 1 h before intradermal treatment. Five weaners, including an animal from each treatment, were run in each pen. Neutrophil to ly..View full abstract
This work was commissioned by Australian Wool Innovation and funded by Australian tax payers and woolgrowers through Australian Wool Innovation. The assistance of Rob Powell with mulesing and administration of intradermal treatments and the dedicated technical assistance of Matt Reed, Jim Lea, Dom Niemeyer, Sue Belson, Troy Kalinowski, Remi Climent and Francois Brard are gratefully acknowledged.