The total synthesis of alkaloids (-)-histrionicotoxin 259A, 285C and 285E
CJ Smith, AB Holmes, NJ Press
CHEMICAL COMMUNICATIONS | ROYAL SOC CHEMISTRY | Published : 2002
The first total syntheses of three "unsymmetrical" (i.e. different terminal groups in the side chains) members of the histrionicotoxin family of alkaloids have been accomplished via stepwise introduction of the two side chain moieties onto a common tricyclic core.