Journal article

Effects of psilocybin on time perception and temporal control of behaviour in humans

Marc Wittmann, Olivia Carter, Felix Hasler, B Rael Cahn, Ulrike Grimberg, Philipp Spring, Daniel Hell, Hans Flohr, Franz X Vollenweider

JOURNAL OF PSYCHOPHARMACOLOGY | SAGE PUBLICATIONS LTD | Published : 2007

Abstract

Hallucinogenic psilocybin is known to alter the subjective experience of time. However, there is no study that systematically investigated objective measures of time perception under psilocybin. Therefore, we studied dose-dependent effects of the serotonin (5-HT)2A/1A receptor agonist psilocybin (4-phosphoryloxy-N, N-dimethyltryptamine) on temporal processing, employing tasks of temporal reproduction, sensorimotor synchronization and tapping tempo. To control for cognitive and subjective changes, we assessed spatial working memory and conscious experience. Twelve healthy human volunteers were tested under placebo, medium (115 microg/kg), and high (250 microg/kg) dose conditions, in a double-..

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