Risk factors for graft infection in India: A case-control study

Abstract

Aim: To study the demographic, clinical, and microbiological profile and the risk factors for graft infection following penetrating keratoplasty. Methods: 50 eyes of 50 consecutive patients with graft infection after an optical penetrating keratoplasty were included as cases; 50 eyes of 50 patients with no graft infection were included as controls. The main variables evaluated in this study included the clinical and microbiological profile, sociodemographic status, suture related problems, persistent epithelial defects, and ocular surface disorders. Results: Cultures were positive in 43 (86%) eyes and Staphylococcus epidermidis (67.4%) was the most common organism isolated. Infection could b..