The prevalence and risk factors of retinal microvascular abnormalities in older persons - The cardiovascular health study

TY Wong; R Klein; AR Sharrett; TA Manolio; LD Hubbard; EK Marino; L Kuller; G Burke; RP Tracy; JF Polak; JS Gottdiener; DS Siscovick

Journal article

The prevalence and risk factors of retinal microvascular abnormalities in older persons - The cardiovascular health study

TY Wong, R Klein, AR Sharrett, TA Manolio, LD Hubbard, EK Marino, L Kuller, G Burke, RP Tracy, JF Polak, JS Gottdiener, DS Siscovick

OPHTHALMOLOGY | ELSEVIER SCIENCE INC | Published : 2003

DOI: 10.1016/S0161-6420(02)01931-0

Abstract

PURPOSE: To describe the prevalence of retinal microvascular characteristics and their associations with atherosclerosis in elderly, nondiabetic persons. DESIGN AND PARTICIPANTS: Population-based, cross-sectional study comprising 2050 men and women aged 69 to 97 years without diabetes, living in four communities. METHODS: Participants underwent retinal photography and standardized grading of retinal microvascular characteristics, including retinopathy (e.g., microaneurysms, retinal hemorrhages), focal arteriolar narrowing, and arteriovenous nicking. In addition, calibers of retinal arterioles and venules were measured on digitized photographs to obtain an estimate of generalized arteriolar n..

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