Fat Consumption and Its Association With Age-Related Macular Degeneration
Elaine W-T Chong, Luibov D Robman, Julie A Simpson, Allison M Hodge, Khin Zaw Aung, Theresa K Dolphin, Dallas R English, Graham G Giles, Robyn H Guymer
ARCHIVES OF OPHTHALMOLOGY | AMER MEDICAL ASSOC | Published : 2009
OBJECTIVE: To evaluate associations between past dietary fat intake and the prevalence of age-related macular degeneration (AMD). METHODS: Six thousand seven hundred thirty-four participants aged 58 to 69 years in 1990-1994 took part in this cohort study. Participants' nutrient intakes were estimated from a food frequency questionnaire at baseline. At follow-up from 2003 to 2006, digital macula photographs of both eyes were evaluated for early and late AMD signs. Logistic regression was used to estimate odds ratios, with adjustment for age, smoking, and other potential confounders. RESULTS: Higher trans-unsaturated fat intake was associated with an increased prevalence of late AMD; the odds ..View full abstract
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Awarded by National Health and Medical Research Council
This study was supported by the National Health & Medical Research Council Public Health Scholarship (Dr Chong); National Health & Medical Research Council Career Development award (Dr Guymer); Royal Victorian Eye and Ear Hospital Wagstaff fellowship (Dr Robman); and National Health and Medical Research Council Program Grant 209057, Capacity Building Grant 251533, and Enabling Grant 396414 from the National Health and Medical Research Council. The ophthalmic component was funded by the Ophthalmic Research Institute of Australia, John Reid Charitable Trust, and Perpetual Trustees.