Prospects for an influenza vaccine that induces cross-protective cytotoxic T lymphocytes
Lorena E Brown, Anne Kelso
IMMUNOLOGY AND CELL BIOLOGY | WILEY | Published : 2009
Our approach to vaccination against influenza is unique. For no other pathogen do we construct and produce a new vaccine every year in the face of uncertainty about the strains that will be circulating when it is used. The huge global cooperative effort that underpins this process reflects our awareness of the need to control this major pathogen. Moreover, the threat of devastation by a pandemic due to a newly emerging viral subtype has triggered an intense effort to improve and accelerate the production of vaccines for use if a pandemic arises. However, type A influenza viruses responsible for seasonal epidemics and those with the potential to cause a pandemic share amino acid sequences tha..View full abstract
The Melbourne WHO Collaborating Centre for Reference and Research in Influenza is supported by the Australian Government Department of Health and Ageing.