Journal article

Artificial aortic valves: An overview

YS Morsi, IE Birchall, FL Rosenfeldt

INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS | SAGE PUBLICATIONS LTD | Published : 2004

Abstract

This review discusses strategies that may address some of the limitations associated with replacing diseased or dysfunctional aortic valves with mechanical or tissue valves. These limitations range from structural failure and thromboembolic complications associated with mechanical valves to a limited durability and calcification with tissue valves. In pediatric patients there is an issue with the inability of substitutes to grow with the recipient. The emerging science of tissue engineering potentially provides an attractive alternative by creating viable tissue structures based on a resorbable scaffold. Morphometrically precise, biodegradable polymer scaffolds may be fabricated from data ob..

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