Journal article
A microreactor with thousands of subcompartments: Enzyme-loaded liposomes within polymer capsules
B Stadler, R Chandrawati, AD Price, SF Chong, K Breheney, A Postma, LA Connal, AN Zelikin, F Caruso
Angewandte Chemie International Edition | Published : 2009
Abstract
Fully loaded: Noncovalent anchoring of liposomes into polymer multilayered films with cholesterol-modified polymers allows the preparation of capsosomes - liposomecompartmentalized polymer capsules (see picture). A quantitative enzymatic reaction confirmed the presence of active cargo within the capsosomes and was used to determine the number of subcompartments within this novel biomedical carrier system. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.