Journal article

The Cardiorenal Syndrome

Claudio Ronco, Chang-Yin Chionh, Mikko Haapio, Nagesh S Anavekar, Andrew House, Rinaldo Bellomo



The term 'cardiorenal syndrome' (CRS) has increasingly been used in recent years without a constant meaning and a well-accepted definition. To include the vast array of interrelated derangements, and to stress the bidirectional nature of the heart-kidney interactions, the classification of the CRS today includes 5 subtypes whose etymology reflects the primary and secondary pathology, the time frame and simultaneous cardiac and renal codysfunction secondary to systemic disease. The CRS can generally be defined as a pathophysiological disorder of the heart and kidneys whereby acute or chronic dysfunction in one organ may induce acute or chronic dysfunction in the other organ. Type I CRS reflec..

View full abstract

University of Melbourne Researchers