Neurobehavior at Term and White and Gray Matter Abnormalities in Very Preterm Infants

NC Brown; TE Inder; MJ Bear; RW Hunt; PJ Anderson; LW Doyle

Journal article

Neurobehavior at Term and White and Gray Matter Abnormalities in Very Preterm Infants

NC Brown, TE Inder, MJ Bear, RW Hunt, PJ Anderson, LW Doyle

Journal of Pediatrics | Published : 2009

DOI: 10.1016/j.jpeds.2009.01.038

Abstract

Objective: To examine the relationship between very preterm infant neurobehavior at term and concurrent magnetic resonance-defined cerebral abnormalities. Study design: 168 very preterm infants (birth weight <1250 g or gestation <30 weeks) were examined at term with 2 standardized neurobehavioral assessments, the Revised Hammersmith Neonatal Neurological Examination and the Neonatal Intensive Care Unit Network Neurobehavioral Scale. The relationship between composite neurobehavioral scores and qualitative white and gray matter abnormalities on magnetic resonance imaging was determined. Results: Poorer neurobehavioral performance related to magnetic resonance-defined cerebral abnormalities. C..

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University of Melbourne Researchers

Lex Doyle Author

Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

Supported by partial funding from the National Health and Medical Research Council (NHMRC project grant 237117). N.B. supported by scholarship from the University of Melbourne, the Royal Women's Hospital and the Murdoch Children's Research Institute, Melbourne, Australia. The authors declare no real or perceived conflicts of interest.