Visualizing CTL activity for different CD8( ) effector T cells supports the idea that lower TCR/epitope avidity may be advantageous for target cell killing

MR Jenkins; NL La Gruta; PC Doherty; JA Trapani; SJ Turner; NJ Waterhouse

Journal article

Visualizing CTL activity for different CD8( ) effector T cells supports the idea that lower TCR/epitope avidity may be advantageous for target cell killing

MR Jenkins, NL La Gruta, PC Doherty, JA Trapani, SJ Turner, NJ Waterhouse

Cell Death & Differentiation | NATURE PUBLISHING GROUP | Published : 2009

DOI: 10.1038/cdd.2008.176

University of Melbourne Researchers

Stephen Turner Author Microbiology and Immunology

Misty Jenkins Author Medical Biology (W.E.H.I.)

Nicole La Gruta Author Microbiology and Immunology

Peter Doherty Author Microbiology and Immunology

Joseph Trapani Author The Sir Peter MacCallum Department of Oncology

Grants

Funding Acknowledgements

This work was supported by an Australian Postgraduate Award to MRJ, a Burnet Award from the National Health and Medical Research Council of Australia (NHMRC) to PCD, RD Wright Fellowships from the NHMRC to NJW and NLG and a Pfizer Senior Research Fellowship to SJT. JAT is a senior principal research fellow of the NHMRC.