Theory of mind impairment in schizophrenia: Meta-analysis

Abstract

There is now substantial evidence for Theory of mind (ToM) impairment in schizophrenia. Despite this, we know little about how dynamic (state) variables and broad clinical, cognitive and medication characteristics moderate the precise magnitude of the observed ToM deficit during task performance. Meta-analyses were conducted using 36 studies that reported continuous data regarding ToM performances of schizophrenia patients and healthy control subjects. These 36 studies included 1,181 (67% male) patients with schizophrenia and 936 (58.3% male) healthy control subjects. Individual analyses were also conducted for the Hinting and the Eyes tasks. The effects of moderator variables were studied b..