Journal article
Assessing the impact of FDG-PET in the management of anal cancer
BT Nguyen, DL Joon, V Khoo, G Quong, M Chao, M Wada, ML Joon, A See, M Feigen, K Rykers, C Kai, E Zupan, A Scott
Radiotherapy and Oncology | Published : 2008
Abstract
Purpose: To assess the utility of FDG-PET in anal cancer for staging and impact on radiotherapy planning (RTP), response and detection of recurrent disease. Methods and materials: Fifty histopathological anal cancer patients were reviewed between 1996 and 2006. The median age was 58 years (range 36-85) with 19 males:31females. Clinical assessment with CT was compared to PET. Impact on management, disease response, recurrence and metastases was evaluated. Results: The non-PET staging was Stage I(8), Stage II(18), Stage III(22), and Stage IV(2)s. The primary was strongly FDG avid in 98% with non-excised tumors compared to CT (58%). PET upstaged 17% with unsuspected pelvic/inguinal nodal diseas..
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