Journal article
Retinal vascular caliber and diabetes in a multiethnic asian population
VSE Jeganathan, C Sabanayagam, ES Tai, J Lee, E Lamoureux, C Sun, R Kawasaki, TY Wong
Microcirculation | Published : 2009
Abstract
Objective: The aim of this study was to examine the relationship of retinal vascular caliber with diabetes and impaired fasting glucose (IFG) in a multiethnic Asian population. Methods: This work was a population-based cross-sectional study comprising 3,404 Singaporean Chinese, Indian, and Malay participants. Retinal arteriolar and venular diameters, CRAE and CRVE, respectively were measured from digital retinal photographs. Diabetes was defined as physician-diagnosis of diabetes, self-reported use of diabetic medication, or fasting plasma glucose (FPG) ≥7 mmol/L; IFG as FPG 6.1-6.9 mmol/L. Results: After adjusting for age, gender, ethnicity, systolic blood pressure, body mass index, total c..
View full abstractGrants
Awarded by Biomedical Research Council
Awarded by National Medical Research Council
Awarded by Singapore Bio Imaging Consortium
Funding Acknowledgements
This work was supported by Biomedical Research Council grants (nos. 03/1/27/18/216 and 08/1/35/ 19/550), a National Medical Research Council grant (no. 0838/2004), and the Singapore Bio Imaging Consortium (C-011/2006). The authors thank the staff and participants in the Singapore Prospective Study Program and the Singapore Cardiovascular Cohort Study for their important contributions. The authors also thank Mya Sandar, MBBS, Ms. Maisie Ho, and Sangeetha Nagarajah for study coordination and data management, and Ms. Lauren Hodgson, Ms. Kim Yu Lee, and Jessica Alessi for retinal vessel grading and grading data management.