Journal article

A disturbed sense of self in the psychosis prodrome: Linking phenomenology and neurobiology

B Nelson, A Fornito, BJ Harrison, M Yuecel, LA Sass, AR Yung, A Thompson, SJ Wood, C Pantelis, PD McGorry

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2009

Abstract

Interest in the early phase of psychotic disorders has risen dramatically in recent years. Neurobiological investigations have focused specifically on identifying brain changes associated with the onset of psychosis. The link between these neurobiological findings and the complex phenomenology of the early psychosis period is not well understood. In this article, we re-cast some of these observations, primarily from neuroimaging studies, in the context of phenomenological models of "the self" and disturbance thereof in psychotic illness. Specifically, we argue that disturbance of the basic or minimal self ("ipseity"), as articulated in phenomenological literature, may be associated with abno..

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Grants

Awarded by National Health and Medical Research Council (NHMRC)


Awarded by National Health and Medical Research Council of Australia (NHMRC) Training Award


Awarded by NHMRC Clinical Career Development Award


Funding Acknowledgements

B.N. was supported by a Ronald Philip Griffith Fellowship and a NARSAD Young Investigator Award. A.F. was supported by a National Health and Medical Research Council (NHMRC) CJ Martin Fellowship (ID: 454797). B.J.H. was supported by a National Health and Medical Research Council of Australia (NHMRC) Training Award (ID: 400420). S.J.W. was supported by a NHMRC Clinical Career Development Award. M.Y. was supported by a NHMRC Clinical Career Development Award (ID: 509345). Research in early psychosis was supported by a NHMRC Program Grant to P.D.M., C.P. and A.R.Y. (ID: 350241).