On Extremum Seeking in Bioprocesses with Multivalued Cost Functions
Georges Bastin, Dragan Nesic, Ying Tan, Iven Mareels
BIOTECHNOLOGY PROGRESS | WILEY | Published : 2009
Finding optimal operating modes for bioprocesses has been, for a long time, a relevant issue in bioengineering. The problem is of special interest when it implies the simultaneous optimization of competing objectives. In this paper, we address the problem of finding optimal steady states that achieve the best tradeoff between yield and productivity by using nonmodel-based extremum-seeking control with semiglobal practical stability and convergence properties. A special attention is paid to processes with multiple steady states and multivalued cost functions.
Awarded by Belgian Programme on Interuniversity Attraction Poles
This work was supported by the Belgian Programme on Interuniversity Attraction Poles (IAP V/22) and by National ICT Australia (NlCTA).