Journal article

On Extremum Seeking in Bioprocesses with Multivalued Cost Functions

Georges Bastin, Dragan Nesic, Ying Tan, Iven Mareels

BIOTECHNOLOGY PROGRESS | WILEY | Published : 2009

Abstract

Finding optimal operating modes for bioprocesses has been, for a long time, a relevant issue in bioengineering. The problem is of special interest when it implies the simultaneous optimization of competing objectives. In this paper, we address the problem of finding optimal steady states that achieve the best tradeoff between yield and productivity by using nonmodel-based extremum-seeking control with semiglobal practical stability and convergence properties. A special attention is paid to processes with multiple steady states and multivalued cost functions.

Grants

Awarded by Belgian Programme on Interuniversity Attraction Poles


Funding Acknowledgements

This work was supported by the Belgian Programme on Interuniversity Attraction Poles (IAP V/22) and by National ICT Australia (NlCTA).