Journal article

Retinal Vascular Changes and Diabetic Retinopathy

Thanh T Nguyen, Tien Yin Wong

CURRENT DIABETES REPORTS | CURRENT MEDICINE GROUP | Published : 2009

Abstract

Recent studies support the concept that the retinal vasculature may provide a summary measure of lifetime exposure to the effects of hyperglycemia. Advances in retinal photographic techniques and in image analysis have allowed objective and precise in vivo measurement of retinal vascular changes. In particular, quantitative assessment of retinopathy signs and measurement of retinal vascular caliber have greatly increased our knowledge of early microcirculatory alterations in prediabetes, diabetes, and diabetic micro- and macrovascular complications. Data from recent population-based studies suggest that retinal arteriolar and venular caliber changes reflect different pathophysiologic process..

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