The conserved metalloprotease invadolysin localizes to the surface of lipid droplets
Neville Cobbe, Kathryn M Marshall, Shubha Gururaja Rao, Ching-Wen Chang, Francesca Di Cara, Edward Duca, Sharron Vass, Adam Kassan, Margarete MS Heck
Journal of Cell Science | COMPANY OF BIOLOGISTS LTD | Published : 2009
Awarded by EU
The authors would like to express their gratitude to Bill Earnshaw and Mike Cousin for interesting and relevant discussions, as well as to Paddy Hadoke, Damien Hudson and Heck lab members for feedback on the manuscript. We are grateful to Grant Sellar, Laura Machesky, David Melton, Bill Earnshaw, Jim Ross and Adriano Rossi for cell lines and cultures. Albert Pol (Barcelona) was extremely helpful in advising on the isolation of lipid droplets from cultured cells. Walid Maalouf and Sari Pennings provided assistance with OptiGrid Structured Illumination Microscopy. This work was supported by a Wellcome Trust University Award to M. M. S. H., a postdoctoral fellowship from Medical Research Scotland to K. M. M., and a Darwin Trust PhD studentship to S. G. R. Work with orang-utan cell lines was supported by EUPRIM-Net under the EU contract RII3-026155 of the 6th Framework Programme. Deposited in PMC for release after 6 months.