Journal article

Effect of topical alkane vapocoolant spray on pain with intravenous cannulation in patients in emergency departments: randomised double blind placebo controlled trial

Ramzi Hijazi, David Taylor, Joanna Richardson

BMJ-BRITISH MEDICAL JOURNAL | BMJ PUBLISHING GROUP | Published : 2009

Abstract

OBJECTIVE: To assess the efficacy, acceptability, and safety of a topical alkane vapocoolant in reducing pain during intravenous cannulation in adults. DESIGN: Randomised double blind placebo controlled trial. SETTING: Emergency department of a metropolitan teaching hospital. PARTICIPANTS: 201 adult patients (54% male), mean (SD) age 58.2 (19.5) years, who required intravenous cannulation. INTERVENTIONS: Less than 15 seconds before cannulation, the skin area was sprayed with either water (control, n=98) or vapocoolant (intervention, n=103), from a distance of 12 cm for 2 seconds. The intervention spray was a blend of propane, butane, and pentane. MAIN OUTCOME MEASURES: Pain with cannulation ..

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University of Melbourne Researchers