Theileria apicoplast as a target for chemotherapy

Abstract

Theileria parasites cause severe bovine disease and death in a large part of the world. These apicomplexan parasites possess a relic plastid (apicoplast), whose metabolic pathways include several promising drug targets. Putative inhibitors of these targets were screened, and we identified antiproliferative compounds that merit further characterization Copyright ©2009, American society tor Micromology. All Rights Reserved.