Maternal responses to adolescent positive affect are associated with adolescents' reward neuroanatomy
Sarah Whittle, Marie BH Yap, Murat Yuecel, Lisa Sheeber, Julian G Simmons, Christos Pantelis, Nicholas B Allen
SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE | OXFORD UNIV PRESS | Published : 2009
The development of reward-based learning and decision-making, and the neural circuitry underlying these processes, appears to be influenced negatively by adverse child-rearing environments characterized by abuse and other forms of maltreatment. No research to-date has investigated whether normative variations in the child-rearing environment have effects on adolescent brain structure. We examined whether normative variations in maternal responses to adolescents' positive affective behavior were associated with morphometric measures of the adolescents' affective neural circuitry, namely the amygdala, orbitofrontal cortex (OFC), and anterior cingulate cortex (ACC). Healthy adolescents (N = 113..View full abstract
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Awarded by National Health and Medical Research Council of Australia
We thank the Brain Research Institute for support in acquiring the neuroimaging data, and the Oregon Research Institute for its role in the coding of family interaction data. Neuroimaging analysis was facilitated by the Neuropsychiatry Imaging Laboratory managed by Ms. Bridget Soulsby at the Melbourne Neuropsychiatry Centre. ORYGEN Research Centre and the Colonial Foundation; Neurosciences Victoria; Australian Research Council Postdoctoral Fellowship ( to S. W.); a Centre for Clinical Research Excellence Postdoctoral Fellowship ( to M. B. H. Y.); National Health and Medical Research Council of Australia Program Grant I. D. 350241 ( to M. Y.).