Journal article

Epidemiology of Septic Acute Kidney Injury

Ambica Parmar, Christoph Langenberg, Li Wan, Clive N May, Rinaldo Bellomo, Sean M Bagshaw

CURRENT DRUG TARGETS | BENTHAM SCIENCE PUBL LTD | Published : 2009

Abstract

The incidence of sepsis and acute kidney injury (AKI) are increasing in critically ill patients and both portend a higher risk of morbidity and death. Sepsis has consistently been shown to be a key contributing factor for the development of AKI. Numerous observational studies have found septic AKI to be highly common among the critically ill. Septic AKI patients are characterized by important differences in baseline demographics, acuity of illness and treatment intensity when compared with non-septic AKI. In particular, these patients are often older, have a higher prevalence of co-morbid illnesses, and are admitted for medical or emergency surgical indications. These patients show greater a..

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