Journal article
Olfactory dysfunction is associated with subjective memory complaints in community-dwelling elderly individuals
HR Sohrabi, KA Bates, M Rodrigues, K Taddei, SM Laws, NT Lautenschlager, SS Dhaliwal, ANB Johnston, A MacKay-Sim, S Gandy, JK Foster, RN Martins
Journal of Alzheimer S Disease | IOS PRESS | Published : 2009
Abstract
Olfactory dysfunction has been reported in clinical and preclinical phases of Alzheimer's disease. Subjective memory complaints have been proposed as a potential early indicator for increased risk of Alzheimer's disease, but have also been associated with depression, personality characteristics, and health problems. In this study, we aimed to determine which of these putative markers can predict memory complaints in community-dwelling elderly individuals, focusing on olfactory symptoms. A cohort of 144 elderly volunteers (42 males and 102 females), aged 50 to 86, was recruited from an ongoing longitudinal study. Participants were assessed for olfactory capacities (threshold, discrimination, ..
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Awarded by National Institute on Aging
Funding Acknowledgements
Mr. Sohrabi's Ph. D. is supported by a scholarship from the University of Western Australia. This study was funded by grants from the National and Medical Research Council and the McCusker Foundation for Alzheimer's Disease Research (project ID: 52070400). The authors would like to also thank all the participants in this study for their time and effort, Professor Elizabeth Zelinski for providing information and references for the Memory Functioning Questionnaire (MFQ), and Mrs. Shahnaz Zeinali for helping with scoring of the tests.