One-year weight maintenance after significant weight loss in healthy overweight and obese subjects: Does diet composition matter?

Abstract

Background: For many people, maintenance of weight loss is elusive. Whereas high-protein (HP) diets have been found to be superior to high-carbohydrate (HC) diets for weight loss in the short term, their benefits long term are unclear, particularly for weight maintenance. Furthermore, the literature lacks consensus on the long-term effects of an HP diet on cardiovascular disease risk factors. Objective: The objective was to investigate whether macronutrient dietary composition plays a role in weight maintenance and in improvement of cardiovascular disease risk factors. Design: The study comprised 2 phases. Phase 1 featured a verylow-energy diet for 3 mo. In phase 2, the subjects were randoml..