Levels of neuregulin 1 and 3 proteins in Brodmann's area 46 from subjects with schizophrenia and bipolar disorder
Simone Boer, Michael Berk, Brian Dean
NEUROSCIENCE LETTERS | ELSEVIER IRELAND LTD | Published : 2009
Neuregulin (NRG) 1Ialpha and NRG3 proteins levels were measured in Brodmann's area 46 from 20 subjects with schizophrenia, 8 subjects with bipolar 1 disorder and 20 age-sex matched control subjects. Protein levels of both NRG1Ialpha and NRG3 were unchanged in both psychiatric illnesses. These data suggest any change in NRG1Ialpha and NRG3 expression in schizophrenia or bipolar 1 disorder do not result in changes levels in levels of those proteins Brodmann's area 46.
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Awarded by NHMRC
B.D. is a Senior NHMRC Research Fellow (Level 13) (400016). S.B. was a recipient of an Ian Scott Scholarship from The Australian Rotary Health Research Fund. The study was funded in part by Rebecca L. Cooper Medical Research Foundation, NHMRC Project Grants # 193299 and the Operational Infrastructure Support (OIS) from the Victorian State Government.