Relationship between Retinal Structures and Retinal Vessel Caliber in Normal Adolescents
Chameen Samarawickrama, Son C Huynh, Jie Jin Wang, Amy Pai, Nichole Joachim, George Burlutsky, Tien Y Wong, Paul Mitchell
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE | ASSOC RESEARCH VISION OPHTHALMOLOGY INC | Published : 2009
PURPOSE: To describe the normal physiological relationship between retinal arteriolar and venular caliber and retinal nerve fiber layer (RNFL), macular, and optic nerve head parameters. METHODS: The Sydney Childhood Eye Study assessed 2038 adolescents aged 12 years. Retinal vessel calibers were measured from digital fundus photographs using standardized protocols. Optical coherence tomography measurements of RNFL, macular, and optic nerve head parameters were obtained with the Fast-scan protocol of the Stratus OCT (Carl Zeiss Meditec, Inc., Dublin, CA). Mixed model analyses were performed. RESULTS: After adjustment for covariates, each micrometer increase in RNFL thickness was associated wit..View full abstract
Supported by Grant 253732 from the Australian National Health and Medical Research Council, Canberra, Australia.