Determinants of Percentage and Area Measures of Mammographic Density
Jennifer Stone, Ruth ML Warren, Elizabeth Pinney, Jane Warwick, Jack Cuzick
AMERICAN JOURNAL OF EPIDEMIOLOGY | OXFORD UNIV PRESS INC | Published : 2009
Mammographic density is one of the strongest predictors of breast cancer risk. Typically expressed as a percentage of the breast area occupied by radiologically dense tissue on a mammogram, its full value may not be realized because of its negative association with body mass index. A simpler measure of mammographic density, independent of other breast cancer risk factors and equally predictive of risk, would be preferable for risk prediction models. Percentage and area measures of mammographic density were determined for 815 women at high risk for breast cancer from the baseline assessments in the International Breast Cancer Intervention Study I, a trial of tamoxifen for breast cancer preven..View full abstract
Awarded by Cancer Research United Kingdom program
This work was supported by Cancer Research United Kingdom program grant C569/A10404.