Journal article
The hepatocyte growth factor receptor (MET) gene is not associated with refractive error and ocular biometrics in a Caucasian population.
M Schache, CY Chen, M Dirani, PN Baird
Molecular Vision | MOLECULAR VISION | Published : 2009
Abstract
PURPOSE: The purpose of this study was to determine if genetic variants in the hepatocyte growth factor receptor (MET) gene are associated with refractive error and ocular biometric measures in a Caucasian cohort. METHODS: A case-control association study using 818 Caucasian adults (37.2% male, 62.8% female; average age: 51.21+/-17.17 years) was undertaken. All individuals were genotyped for 16 tag single nucleotide polymorphisms (tSNPs) across the MET gene region. Myopia was defined as -0.5 DS or worse in both eyes and divided into high myopia (
Grants
Awarded by National Health and Medical Research Council
Funding Acknowledgements
The authors wish to thank participants from the GEM study who made this work possible. The authors would also like to thank the Australian Twin Registry and the Melbourne Excimer Laser Group (MELG) for their assistance with recruitment. This work was supported by the Australian Federal Government through a National Health and Medical Research Project Grant (#529912) as well by the Angior Family Foundation. The authors wish to state that there are no conflicts of interest.