The role of acetaldehyde and glycerol in the adaptation to ethanol stress of Saccharomyces cerevisiae and other yeasts
Frank Vriesekoop, Cornelia Haass, Neville B Pamment
FEMS YEAST RESEARCH | WILEY-BLACKWELL PUBLISHING, INC | Published : 2009
Ethanol inhibition is a commonly encountered stress condition during typical yeast fermentations and often results in reduced fermentation rates and production yields. While past studies have shown that acetaldehyde addition has a significant ameliorating effect on the growth of ethanol-stressed Saccharomyces cerevisiae, this study investigated the potential ameliorating effect of acetaldehyde on a wide range of ethanol-stressed yeasts. Acetaldehyde does not appear to be a universal ameliorating agent for yeasts exposed to ethanol stress. It is also shown that as a result of an ethanol stress, most yeasts rapidly produce glycerol as an alternative means of NAD(+) regeneration rather than hav..View full abstract
We would like to thank Gregoria Luna for her technical assistance and Garry Menz for his statistical assistance. The project was funded in part by a grant from the Australian Research Council.