Journal article

Altered M-1 Muscarinic Acetylcholine Receptor (CHRM1)-G alpha(q/11) Coupling in a Schizophrenia Endophenotype

Hasib Salah-Uddin, Elizabeth Scarr, Geoffrey Pavey, Kriss Harris, Jim J Hagan, Brian Dean, RA John Challiss, Jeannette M Watson

Neuropsychopharmacology | NATURE PUBLISHING GROUP | Published : 2009

DOI: 10.1038/npp.2009.41

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Keywords

Neurosciences
Phenotype
Neurosciences & Neurology
Dysfunction
Guanosine 5'-O-(3-Thiotriphosphate)
Pirenzepine
Protein Binding
Young Adult
Adult
Middle Aged
[s-35]-Gtp Gamma S Immunocapture
G Alpha(q/11) Protein
Female
[h-3]-Pirenzepine Binding
Membranes
Prefrontal Cortex
Science & Technology
Receptor, Muscarinic M1
Subtype
Piperidines
Binding
Tritium
Muscarinic Acetylcholine Receptor (chrm)
Availability
Expression
Male
Muscarinic Antagonists
Agonist
Aged
Psychiatry
Oxotremorine
Sulfur Radioisotopes
Life Sciences & Biomedicine
Human Brain Tissue
Receptors, Muscarinic
Pharmacology & Pharmacy
Mutant Mice
Muscarinic Agonists
Cell Membrane
Brain
Humans
Schizophrenia
Gtp-Binding Protein Alpha Subunits, Gq-G11