Journal article

Principles of design and biological approaches for improving the selectivity of cochlear implant electrodes

Stephen J O'Leary, Rachael R Richardson, Hugh J McDermott

JOURNAL OF NEURAL ENGINEERING | IOP PUBLISHING LTD | Published : 2009

Abstract

The perceptual performance of cochlear implant recipients seems to have reached a plateau in recent years. This may be attributable to inadequate neural selectivity of available intracochlear electrodes, caused by current spread and electrode interactions. Attempts to improve electrode selectivity have included manipulating the number and configuration of electrodes that are stimulated at any one time, displacing perilymph from the cochlea to restrict current flow along the cochlea, and reducing the distance between electrodes and neurons. One experimental approach by which the distance between neurons and electrodes may be reduced is to use neurotrophic factors to promote the regeneration o..

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Grants

Funding Acknowledgements

We wish to thank Peter Seligman from Cochlear Corporation for helpful critique of this work. Dr Andrew Wise is thanked for providing figure 1. We also wish to thank our funding bodies, including the National Health and Medical Research Council of Australia, the Stravos N Niarchos Foundation (USA), the Garnett Pass and Rodney Williams Memorial Foundation (Australia), the Royal National Institutes of the Deaf (UK), and the Royal Victorian Eye and Ear Hospital.