Journal article

Intakes of fruit, vegetables, and carotenoids and renal cell cancer risk: A pooled analysis of 13 prospective studies

EL Jung, S Männistö, D Spiegelman, DJ Hunter, L Bernstein, PA Van Den Brandt, JE Buring, E Cho, DR English, A Flood, JL Freudenheim, GG Giles, E Giovannucci, N Håkansson, PL Horn-Ross, EJ Jacobs, MF Leitzmann, JR Marshall, ML McCullough, AB Miller Show all

Cancer Epidemiology Biomarkers and Prevention | Published : 2009

Abstract

Fruit and vegetable consumption has been hypothesized to reduce the risk of renal cell cancer. We conducted a pooled analysis of 13 prospective studies, including 1,478 incident cases of renal cell cancer (709 women and 769 men) among 530,469 women and 244,483 men followed for up to 7 to 20 years. Participants completed a validated food-frequency questionnaire at baseline. Using the primary data from each study, the study-specific relative risks (RR) were calculated using the Cox proportional hazards model and then pooled using a random effects model. We found that fruit and vegetable consumption was associated with a reduced risk of renal cell cancer. Compared with <200 g/d of fruit and veg..

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University of Melbourne Researchers