Progression of chronic periodontitis can be predicted by the levels of Porphyromonas gingivalis and Treponema denticola in subgingival plaque
SJ Byrne, SG Dashper, IB Darby, GG Adams, B Hoffmann, EC Reynolds
ORAL MICROBIOLOGY AND IMMUNOLOGY | WILEY | Published : 2009
INTRODUCTION: Chronic periodontitis is an inflammatory disease of the supporting tissues of the teeth associated with bacteria. Diagnosis is achieved retrospectively by clinical observation of attachment loss. Predicting disease progression would allow for targeted preventive therapy. The aim of this study was to monitor disease progression in patients on a maintenance program and determine the levels of specific bacteria in subgingival plaque samples and then examine the ability of the clinical parameters of disease and levels of specific bacteria in the plaque samples to predict disease progression. METHODS: During a 12-month longitudinal study of 41 subjects, 25 sites in 21 subjects exper..View full abstract
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Awarded by NHMRC
Nada Slakeski, Luan Ngo and Andrei Locke are thanked for their excellent clinical and technical assistance. Samantha Byrne was the recipient of an NHMRC postgraduate scholarship. This research was supported by NHMRC Oral Health Research grant #219189.