Australasian resuscitation of sepsis evaluation (ARISE): A multi-centre, prospective, inception cohort study

SL Peake; M Bailey; R Bellomo; PA Cameron; A Cross; A Delaney; S Finfer; A Higgins; DA Jones; JA Myburgh; GA Syres; SAR Webb; P Williams

Journal article

Australasian resuscitation of sepsis evaluation (ARISE): A multi-centre, prospective, inception cohort study

SL Peake, M Bailey, R Bellomo, PA Cameron, A Cross, A Delaney, S Finfer, A Higgins, DA Jones, JA Myburgh, GA Syres, SAR Webb, P Williams

Resuscitation | ELSEVIER IRELAND LTD | Published : 2009

DOI: 10.1016/j.resuscitation.2009.03.008

Abstract

Aim: Determine current resuscitation practices and outcomes in patients presenting to the emergency department (ED) with sepsis and hypoperfusion or septic shock in Australia and New Zealand (ANZ). Methods: Three-month prospective, multi-centre, observational study of all adult patients with sepsis and hypoperfusion or septic shock in the ED of 32 ANZ tertiary-referral, metropolitan and rural hospitals. Results: 324 patients were enrolled (mean [SD] age 63.4 [19.2] years, APACHE II score 19.0 [8.2], 52.5% male). Pneumonia (n = 138/324, 42.6%) and urinary tract infection (n = 98/324, 30.2%) were the commonest sources of sepsis. Between ED presentation and 6 hours post-enrolment (T6hrs), 44.4%..

View full abstract

University of Melbourne Researchers

Anthony Cross Author

Daryl Jones Author

Grants

Funding Acknowledgements

The ARISE observational study was supported by a grant from the Intensive Care Foundation and an unrestricted grant from Edwards Life Sciences. The support and commitment of the research coordinators and principle investigators at each of the participating sites is also gratefully acknowledged.