Journal article
Genome-wide survey of SNP variation uncovers the genetic structure of cattle breeds
RA Gibbs, JF Taylor, CP Van Tassell, W Barendse, KA Eversole, CA Gill, RD Green, DL Hamernik, SM Kappes, S Lien, LK Matukumalli, JC McEwan, LV Nazareth, RD Schnabel, GM Weinstock, DA Wheeler, P Ajmone-Marsan, W Barends, PJ Boettcher, AR Caetano Show all
Science | AMER ASSOC ADVANCEMENT SCIENCE | Published : 2009
Abstract
The imprints of domestication and breed development on the genomes of livestock likely differ from those of companion animals. A deep draft sequence assembly of shotgun reads from a single Hereford female and comparative sequences sampled from six additional breeds were used to develop probes to interrogate 37,470 single-nucleotide polymorphisms (SNPs) in 497 cattle from 19 geographically and biologically diverse breeds. These data show that cattle have undergone a rapid recent decrease in effective population size from a very large ancestral population, possibly due to bottlenecks associated with domestication, selection, and breed formation. Domestication and artificial selection appear to..
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Awarded by National Institute of General Medical Sciences
Funding Acknowledgements
The Bovine Hapmap Consortium funded by the National Human Genome Research Institute of the National Institutes of Health, U.S. Department of Agricultures Agricultural Research Service (USDA-ARS) and Cooperative State Research, Education and Extension Service (USDA CSREES), the Research Council of Norway, as well as: American Angus Association, American Hereford Association, American Jersey Cattle Association, AgResearch (New Zealand), Beef CRC and Meat and Livestock Australia for the Australian Brahman Breeders Association, Beefmaster Breeders United, The Brazilian Agricultural Research Corporation (Embrapa), Brown Swiss Association, Commonwealth Scientific and Industrial Research Organization, Dairy InSight, GENO Breeding and Artificial Insemination Association-Norway, Herd Book/France Limousin Selection, Holstein Association USA, International Atomic Energy Agency (IAEA)-United Nations Food and Agriculture Organization (FAO)/IAEA Vienna, International Livestock Research Institute-Kenya, Italian Piedmontese Breeders-Parco Tecnologico Padano, Italian Romagnola Society-Universita Cattolica del Sacro Cuore, Livestock Improvement Corporation, Meat and Wool New Zealand. North American Limousin Foundation, Red Angus Association of America, Roslin Institute for UK Guernsey, and Sygen (now Genus). See SOM for additional acknowledgements. The genome sequence (AAFC03000000) and SNPs (SOM) are available from NCBI.