Registry- and clinic-based analyses of birth defects and syndromes associated with cleft lip/palate in Victoria, Australia

Abstract

Objective: To study the birth defects and syndromes associated with cleft lip and/or cleft palate in children born from 2000 through 2002 in Victoria, Australia, comparing data from the birth defects registry and detailed clinical assessment. Design, Setting, and Participants: Data recorded in the Victorian Birth Defects Register were retrieved for all children with cleft lip and/or palate born from 2000 through 2002. In parallel, a cohort of children with clefts was recruited from the two cleft centers in Victoria. Clinical data were collected using structured parental interview, clinical/dysmorphologic examination, and file review. Results: Victorian Birth Defects Register records of 312 c..