Implementation of ironXS: a study of the acceptability and feasibility of genetic screening for hereditary hemochromatosis in high schools
MB Delatycki, M Wolthuizen, V Collins, E Varley, J Craven, KJ Allen, MA Aitken, L Bond, PJ Lockhart, GR Wilson, I Macciocca, SA Metcalfe
CLINICAL GENETICS | WILEY-BLACKWELL PUBLISHING, INC | Published : 2010
Hereditary hemochromatosis (HH), most often due to HFE C282Y homozygosity, is an iron overload disorder that can result in severe morbidity including hepatic cirrhosis. Predisposition to HH is easily diagnosed and morbidity is preventable by maintaining normal body iron and thus calls have been made to introduce community screening. The current study has been designed to assess the acceptability and feasibility of HH screening in high schools. Students (mostly 15-16 years of age) watched a purpose-designed DVD for education about HH. Those with parental consent were then offered cheek-brush screening for C282Y. Students completed a questionnaire prior to screening. The program was offered to..View full abstract
Awarded by National Health and Medical Research Council
Funding for this study has been obtained from the National Health and Medical Research Council (491224), the Jack Brockhoff Foundation and the Murdoch Childrens Research Institute. MBD is a Practitioner Fellow (546452), KJA is a Career Development Award recipient (364460) and PJL is an RD Wright Fellow (334346), all awards being from the National Health and Medical Research Council.