Journal article

Learning from Errors: Error-Related Neural Activity Predicts Improvements in Future Inhibitory Control Performance

Robert Hester, Janelle Madeley, Kevin Murphy, Jason B Mattingley

JOURNAL OF NEUROSCIENCE | SOC NEUROSCIENCE | Published : 2009

Abstract

Failure to adapt performance following an error is a debilitating symptom of many neurological and psychiatric conditions. Healthy individuals readily adapt their behavior in response to an error, an ability thought to be subserved by the posterior medial frontal cortex (pMFC). However, it remains unclear how humans adaptively alter cognitive control behavior when they reencounter situations that were previously failed minutes or days ago. Using functional magnetic resonance imaging, we examined neural activity during a Go/No-go response inhibition task that provided the opportunity for participants to learn from their errors. When they failed to inhibit their response, they were shown the s..

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Grants

Awarded by Australian Research Council


Awarded by National Health and Medical Research Council


Funding Acknowledgements

This research was supported by Australian Research Council Grant DP0556602 ( R. H.) and National Health and Medical Research Council Fellowship 519730 ( R. H.). The assistance of Drs. Katie McMahon, Mark Strudwick, and Matt Meredith (Wesley Hospital) and of Dr. Mark Bellgrove, Felicity Brown, and Ashley Skilleter is gratefully acknowledged.