Journal article

High Molecular Weight Gingipains from Porphyromonas gingivalis Induce Cytokine Responses from Human Macrophage-Like Cells via a Nonproteolytic Mechanism

Rebecca E Fitzpatrick, Andrea Aprico, Lakshmi C Wijeyewickrema, Charles N Pagel, David M Wong, Jan Potempa, Eleanor J Mackie, Robert N Pike

Journal of Innate Immunity | KARGER | Published : 2009

DOI: 10.1159/000181145

Grants

Awarded by NIDCR NIH HHS

Awarded by NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH

Awarded by NATIONAL INSTITUTE OF DENTAL &CRANIOFACIAL RESEARCH

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Keywords

Virulence Factors
Humans
Porphyromonas Gingivalis
Macrophages
Protein Subunits
Cell Line
Rgpb
Science & Technology
Gingipains
Arg-Gingipain
Protease-Activated Receptors
Interferon-Gamma
Interleukin-1beta
Periodontal Health
Granulocyte-Macrophage Colony-Stimulating Factor
Cysteine Endopeptidases
Bacteroides-Gingivalis
Adhesins, Bacterial
Immunology
Immunity, Innate
Bacteroidaceae Infections
Periodontal Disease
Construction
Inactivation
Up-Regulation
Protease
Proteinases
Cytokines
Pathogenesis
Gingipain Cysteine Endopeptidases
Life Sciences & Biomedicine