Journal article

Clinical predictors of pathological gastro-oesophageal reflux in infants with persistent distress

RG Heine, B Jordan, L Lubitz, M Meehan, AG Catto-Smith

JOURNAL OF PAEDIATRICS AND CHILD HEALTH | WILEY | Published : 2006

Abstract

BACKGROUND: Gastro-oesophageal reflux (GOR) is common in infants with persistent crying. Empirical treatment with antireflux medications is common practice, although on clinical grounds it may be difficult to determine whether GOR is abnormal. AIMS: To examine the diagnostic accuracy of clinical predictors of pathological GOR in infants with persistent crying. METHODS: One hundred and fifty-one infants (82 male; median age 2.5 months, range 0.5-8.2 months) with persistent crying were prospectively studied. Crying and fussing were charted for 24 h, and parents completed a validated questionnaire on reflux symptoms. All infants underwent oesophageal 24-h pH monitoring. RESULTS: Twenty-seven (1..

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