Advances in molecular imaging for the diagnosis of dementia.
Nobuyuki Okamura, Michelle T Fodero-Tavoletti, Yukitsuka Kudo, Christopher C Rowe, Shozo Furumoto, Hiroyuki Arai, Colin L Masters, Kazuhiko Yanai, Victor L Villemagne
Expert Opinion on Medical Diagnostics | Published : 2009
BACKGROUND: There is an urgent need for early diagnosis and treatment of dementia to ease caregiver burden and medical costs associated with the increasing number of affected patients. Molecular imaging with target-specific ligands is contributing to the early diagnosis of dementia and the evaluation of anti-dementia therapy. OBJECTIVE: This article reviews recent advances in the molecular imaging field applied to dementia. To illustrate the utility of molecular imaging in the clinical management of dementia, results from recently published papers using new imaging probes are compared with those from conventional imaging strategies. CONCLUSION: The recent development of β-sheet binding agent..View full abstract