Journal article

COMPARATIVE STUDY OF LDR (MANCHESTER SYSTEM) AND HDR IMAGE-GUIDED CONFORMAL BRACHYTHERAPY OF CERVICAL CANCER: PATTERNS OF FAILURE, LATE COMPLICATIONS, AND SURVIVAL

Kailash Narayan, Sylvia van Dyk, David Bernshaw, Chrishanthi Rajasooriyar, Srinivas Kondalsamy-Chennakesavan

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | ELSEVIER SCIENCE INC | Published : 2009

Abstract

PURPOSE: To compare patterns of failure, late toxicities, and survival in locally advanced cervical cancer patients treated by either low-dose-rate (LDR) or conformal high-dose-rate (HDRc) brachytherapy as a part of curative radiotherapy. MATERIALS AND METHODS: A retrospective comparative study of 217 advanced cervix cancer patients was conducted; 90 of these patients received LDR and 127 received HDRc brachytherapy. All patients were staged using International Federation of Gynecology and Obstetrics (FIGO) rules, had pretreatment magnetic resonance imaging (MRI), and were treated with concurrent cisplatin chemoradiotherapy. Both groups matched for FIGO stage, MRI tumor volume, and uterine i..

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