Journal article

Visuospatial working memory deficits and visual pursuit impairments are not directly related in schizophrenia

Luca Cocchi, Francesca Bosisio, Olivia Carter, Stephen J Wood, Andre Berchtold, Philippe Conus, Alina Orita, Martin Debbane, Francoise Schenk

AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY | SAGE PUBLICATIONS LTD | Published : 2009

Abstract

OBJECTIVE: Patients with schizophrenia show deficits in visuospatial working memory and visual pursuit processes. It is currently unclear, however, whether both impairments are related to a common neuropathological origin. The purpose of the present study was therefore to examine the possible relations between the encoding and the discrimination of dynamic visuospatial stimuli in schizophrenia. METHOD: Sixteen outpatients with schizophrenia and 16 control subjects were asked to encode complex disc displacements presented on a screen. After a delay, participants had to identify the previously presented disc trajectory from a choice of six static linear paths, among which were five incorrect p..

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Grants

Awarded by The Swiss National Foundation for Scientific Research


Funding Acknowledgements

The authors especially thank Professor Pierre Bovet and Dr Francois Grasset for allowing us to test patients under their care and Dr Pascal Vianin and Jerome Favrod for his efficient collaboration. The Swiss National Foundation for Scientific Research supported this study (Professor F. Schenk) 3100A0-105765 and (Dr L. Cocchi) PBLAB-119622 and PBLAB3-119622. Dr Wood is supported by a Clinical Career Development Award from the NHMRC (Australia). Dr P. Conus is supported by the Leenaards Foundation, Switzerland. The Robert Bosch research institute of Lonay (Switzerland) supported this study in providing technological facilities for eye movement recording and analysis.