Journal article

Cognitive complaints after a first seizure in adulthood: Influence of psychological adjustment

Sarah L Velissaris, Sarah J Wilson, Mark R Newton, Samuel F Berkovic, Michael M Saling

EPILEPSIA | WILEY | Published : 2009


PURPOSE: To examine the nature and determinants (biologic and psychological) of cognitive complaints in first-seizure patients. We analyzed this in the context of our previous findings that a sense of loss of control after a newly diagnosed seizure (limited or pervasive) predicts subsequent psychological adjustment trajectories. METHODS: Eighty-five consecutive First Seizure Clinic patients were assessed at 1 and 3 months. Cognitive complaints were evaluated qualitatively, with a semistructured interview, and quantitatively, with the A-B Neuropsychological Assessment Schedule (ABNAS). Objective attentional processing was assessed with reaction time tasks and the Wechsler Adult Intelligence S..

View full abstract


Awarded by ARC Linkage Project

Funding Acknowledgements

This research has been funded by an ARC Linkage Project Grant (LP0453690), GlaxoSmithKline Australia, and The University of Melbourne, Australia. GlaxoSmithKline had no direct involvement in this research. We extend our gratitude to the patients of The First Seizure Clinic, Austin Health, Melbourne, for participating. We also thank Professor Anne Jacoby, Liverpool, for providing the use of the NEWQOL, and Dr John Archer, Melbourne, for his critical review of the manuscript.We confirm that we have read the Journal's position on issues involved in ethical publication and affirm that this report is consistent with those guidelines.Disclosure of conflicts of interest: None of the authors has any conflict of interest to disclose.